Department of Environmental Sciences

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Seminar Abstracts
Environmental Sciences Seminar Abstract            

  ENVIRONMENTAL METAGENOMICS
TIMOTHY M. VOGEL, Ph.D.
Professor, Environmental Microbial Genomics
Department of Electrical Engineering
Ecole Centrale de Lyon, Université de Lyon
Lyon, France

Recent advances in high throughput sequencing have led to the accumulation of metagenomic sequences from a wide range of ecosystems. These metagenomic sequences can now be accessed and exploited by non specialists using different available bioinformatics tools. Recent research into the possible genomic resources from a soil metagenome reinforces the optimism of searching for and finding potential enzymes of interest. The first step includes in silico screening of gene families in order to identify possible targets of interest. The second step includes screening clone libraries for these same (or similar) genes. Some initial work has demonstrated the extensive diversity of different ecosystems, with soil being the most diverse. In addition to biodiversity, different ecosystems might be more appropriate for different families of genes and different functions. Metagenomic approaches to engineered biological systems can also provide insight into the relationship between function and microbial community.


Last updated: 10/03/2011